Bhumiamla
Caplet is a standardized
preparation extracted from Phylanthus
niruri. Phyllanthus primarily
contains lignans (e.g., phyllanthine
and hypophyllanthine), alkaloids,
and bioflavonoids (e.g., quercetin).
Phyllanthus may help decrease
the amount of hepatitis B virus
found in the blood stream. Phyllanthus
blocks DNA polymerase, the enzyme
needed for the hepatitis B virus
to reproduce. In one study, 59%
of those infected with chronic
viral hepatitis B lost one of
the major blood markers of HBV
infection (e.g., hepatitis B surface
antigen) after using phyllanthus
for 30 days.[3] While clinical
studies on the outcome of phyllanthus
and HBV have been mixed, the species
P. urinaria and P. niruri seem
to work better than P. amarus
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Research
Update
Ashwagandha is used in India to
treat mental deficits in geriatric
patients, including amnesia.
Clinical trials and animal research
support the use of ashwagandha
for anxiety, cognitive and neurological
disorders, inflammation, and Parkinson's
disease.
Ashwagandha's chemopreventive
properties make it a potentially
useful adjunct for patients undergoing
radiation and chemotherapy. Ashwaganda
is also used therapeutically as
an adaptogen for patients with
nervous exhaustion, and debility
due to stress, and as an immune
stimulant in patients with low
white blood cell counts.
Researchers from the University
of Leipzig in Germany, wanted
to find out which neurotransmitters
were influenced by ashwagandha.
After injecting some of the chemicals
in ashwagandha into rats, they
later examined slices of their
brain and found an increase in
acetylcholine receptor activity.The
researchers say, "The drug-induced
increase in acetylcholine receptor
capacity might partly explain
the cognition-enhancing and memory-improving
effects of extracts from ashwagandha
observed in animals and humans."
A study done
in 1991 at the Department of
Pharmacology, University of
Texas Health Science Center
indicated that extracts of ashwagandha
had GABA-like activity. This
may account for this herb’s
anti-anxiety effects.
A
2002 laboratory study indicates
ashwagandha stimulates the growth
of axons and dendrites. A 2001
study in rodents showed ashwagandha
had memory boosting ability.
A 2000 study with rodents showed
ashwagandha to have anti-anxiety
and anti-depression effects.
Additional
benefits
One small study found ashwagandha
was able to reduce blood sugar
and cholesterol levels, and had
a diuretic effect.
Results
also indicate that ashwagandha
significantly reduced myocardial
injury and emphasize the beneficial
action of ashwagandha as a cardioprotective
agent.
Side
Effects
Ashwagandha does not have any
significant side effects reported
in the medical literature, but
long term studies are not yet
available. Nevertheless, it is
best to take breaks from use,
for instance, one can take a week
off each month or take ashwagandha
3 or 4 times a week as opposed
to daily.
Supplement
Facts
Serving Size 1 Vegetarian Caplet
Amount Per Caplet
Ashwagandha root extract (5:1
extract) - 300 mg. Suitable for
vegetarians.
Suggested
Use
As an herbal dietary supplement,
take 1 Ashwagandha Caplet 1 to
3 times daily.
Ashwagandha, in some individuals,
may cause drowsiness if taken
during the day. Others who are
restless or anxious may feel a
relaxation but no drowsiness.
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