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Guggul

Guggul Caplet is a standardized preparation extracted from Commiphora mukul, the resin of Guggul tree. The active portion of the plant is the gum resin, which contains guggulsterone. Guggul is known to lower cholesterol and triglycerides, while maintain or improve the HDL to LDL ratio. Its benenfits as a weight-loss and fat burning agent have been well researched and documented in several studies.

Guggul
Guggul - Pure Extract
(300 mg - 60 Capsules)
More Information
Research Update
The effects of the administration of 50 mg of guggulipid or placebo capsules twice daily for 24 weeks were compared as adjuncts to a fruit- and vegetable-enriched prudent diet in the management of 61 patients with hypercholesterolemia (31 in the guggulipid group and 30 in the placebo group) in a randomized, double-blind fashion. Guggulipid decreased the total cholesterol level by 11.7%, the low density lipoprotein cholesterol (LDL) by 12.5%, triglycerides by 12.0%, and the total cholesterol/high density lipoprotein (HDL) cholesterol ratio by 11.1% from the postdiet levels, whereas the levels were unchanged in the placebo group. The HDL cholesterol level showed no changes in the two groups. The lipid peroxides, indicating oxidative stress, declined 33.3% in the guggulipid group without any decrease in the placebo group. The compliance of patients was greater than 96%. The combined effect of diet and guggulipid at 36 weeks was as great as the reported lipid-lowering effect of modern drugs. After a washout period of another 12 weeks, changes in blood lipoproteins were reversed in the guggulipid group without such changes in the placebo group.

Additional benefits
The effectiveness of Commiphora mukul (guggul) for osteoarthritis of the knee: an outcomes study.
The scientists have conducted both preclinical and clinical investigations of guggul for reduction of pain, stiffness, and improved function, and to determine tolerability in older patients with a diagnosis of OA of the knee.
CONCLUSIONS: Overall data indicate significant improvement with guggul for participants during the trial in both scales and objective measures used for assessment purposes. There were no side effects reported during the trial. Guggul appears to be a relatively safe and effective supplement to reduce symptoms of OA.
In addition Guggul is also helpful even in protecting against ailments such as common cold, and various skin, dental and ophthalmic infections. It relaxes the muscles, which helps relieve menstrual pain.
Interactions:
Guggul can be problematic for people being treated for thyroid conditions. Since guggul stimulates production of thyroid hormone, it may alter the dosage requirements for thyroid replacement medication. It can also reduce the availability and effectiveness of the heart medications propranolol (Inderal) and diltiazem (Cardizem). Patients should consult a health care practitioner before taking guggul along with any other herbs or medications

Side Effects
Side effects of guggulipid were headache, mild nausea, eructation, and hiccup in a few patients.

Supplement Facts
Serving Size 1 Vegetarian Caplet
Amount Per Caplet
Guggul extract - 300 mg. Suitable for vegetarians.
Suggested Use
As an herbal dietary supplement, take 1 Guggul Caplet 1 to 3 times daily.
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