Haritaki
Caplet is a standardized
preparation extracted from Terminalia
chebula, the Haritaki fruit
Haritaki fruit pulp helps maintain
regular bowel movements and ensures
the comfort of smooth evacuation.
It is also known as an adaptogen
and hepatoprotective drug.Its
principle constituents contain
chebulagic, chebulinic acid and
corilagin. Its fruits have laxative,
stomachic, tonic and alterative
properties.
The fruit is antiviral, coagulant
and hypoglycemic. It acts as a
gentle laxative and helps in smooth
evacuation.
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| Research
Update
A mention is found in Ayurveda
regarding the use of Terminalia
chebula in disorders of gastrointestinal
motility. Therefore we carried
out this study to evaluate the
effect of Terminalia chebula on
gastric emptying. While planning
the study, metoclopramide - a
prokinetic drug and atropine -
a known antikinetic agent were
incorporated in the study design.
These agents served as tools to
validate the model used to evaluate
gastric emptying and also to compare
the effects of Terminalia chebula.
As there is no pharmacokinetic
data available with regards to
Terminalia chebula, chronic administration
for 15 days was preferred to ensure
adequate concentration of the
agent in the body. On the other
hand, both the standard agents
used for comparison are known
to attain therapeutic concentration
within 30 min of oral/parenteral
administration[10]. The parenteral
route was selected in this study
because the experimental procedure
demands 18 hours fasting prior
to the administration of the test
meal.
The effects of metoclopramide
and atropine on gastric emptying
were as per the expectation. Metoclopramide
increased the percent gastric
emptying significantly as compared
to the normal values whereas atropine
reduced it.
Our study showed that Terminalia
chebula significantly increased
gastric emptying. The enhancement
of gastric emptying was comparable
to that produced by metoclopramide.
This indicates that Terminalia
chebula can be an useful alternative
to the prokinetic drugs available
today.
Additional
benefits
It
is used in hemorrhoids, ophthalmia,
sore throat, dental caries, bleeding
and ulcerated gums, and diseases
of the spleen.
Side
Effects
Haritaki does not have any significant
side effects reported in the medical
literature, but long term studies
are not yet available.
Supplement
Facts
Serving Size 1 Vegetarian Caplet
Amount Per Caplet
Haritaki fruit extract - 300 mg.
Suitable for vegetarians.
Suggested
Use
As an herbal dietary supplement,
take 1 Haritaki Caplet 1 to 3
times daily.
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